The Black Death visited Constantinople eleven times between 1348, when the epidenzic surged iii the Mediterranean world, and 1466 when ouï inquiry ends. We know of these visits from the writings of eye-witnesses who describe their experiences in correspondence written at that titre, in scories reconstructed retrospectively, or in theological discussions. After having related the story of these eleven epidenzic episodes, this article try to catch, through these sources, the inedical perception of the plague by contemporaries, its social consequences and its psychological, spiritual and theological repercussions.